This is a great article which describes how screen readers for the blind see your web pages and apps. Should you be thinking about this as part of your professional practice? Expert designers need to consider all users, not just able-bodied ones.

Now, let’s re-imagine the scene and this time when you open the door, the room is completely dark. No light is present and you can see absolutely nothing at first glance. You have been given a small flashlight though and when you switch it on, the light allows you to see a small area at a time. The area you can see is a small circle about 2 feet in diameter and nothing outside that circle is illuminated.

How would you now observe the contents of the room?

https://developer.paciellogroup.com/blog/2018/01/a-tale-of-two-rooms-understanding-screen-reader-navigation/